Product & ReviewsAntibodies
ER-beta (N-term) Antibody
Product Details
- Cat. No.
- 251152
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Estrogen receptor beta (ER-beta) is a nuclear hormone receptor. ER-beta binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. ER-beta binds DNA as a homodimer, and can form a heterodimer with ESR1. ER-beta interacts with NCOA3, NCOA5 and NCOA6 coactivators, leading to a strong increase of transcription of target genes.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chimpanzee, Human, Monkey, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ER-beta.
- Isotype: Rabbit Ig
- Gene: Q92731
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)