Product & ReviewsAntibodies
ErbB-4 Antibody
Product Details
- Cat. No.
- 251456
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
ErbB-4 (Receptor tyrosine-protein kinase erbB-4) is a tyrosine-protein kinase that regulates development, gene transcription, cell proliferation, differentiation, migration and apoptosis. Erb-4 specifically binds and is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. Interaction with these factors induces cell differentiation. The ErbB-4 intracellular domain is involved in the regulation of cell growth.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Guinea Pig, Horse (Equine), Human, Monkey, Mouse, Pig (Swine), Rabbit (Lapine), Rat, Xenopus
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ErbB-4.
- Isotype: Rabbit Ig
- Gene: Q15303
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)