ESAT-6 Mycobacterium (11G4) Antibody
Product Details
- Cat. No.
- 250322
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
ESAT-6 (6-kDa early secretory antigenic target) from Mycobacterium tuberculosis H37Rv (ATCC 27294) is a secreted tubercular protein that forms a dominant target for cell-mediated immunity in the early phase of infection. The deduced amino acid sequence indicates a molecular mass of 10 kDa. It is present in M. tuberculosis, virulent strains of M. bovis, and in M. flavescens, M. kansasii, M. marinum,and M. szulgai, but not in avirulent M. bovis BCG substrains. This antibody reacts with ESAT-6 in immunoblotting after SDS-PAGE of short-term culture filtrates of M. tuberculosis and virulent strains of M. bovis. The antibody cross-reacts with MPB64 (26 kDa) from certain BCG substrains, with the A, B, and C components of the antigen 85 complex and with MPT51.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bacteria, Mycobacterium tuberculosis
- Antigen: Purified protein derivative (PPD) of tuberculin from M. tuberculosis conjugated with thimerosal N-hydroxysuccinimide ester and adsorbed to aluminum hydroxide gel (4).
- Clone: 11 G4
- Isotype: Mouse IgG1/k
- Gene: P0A564
Handling
- Quantity: 0.2 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)