Product & ReviewsAntibodies
Estrogen Receptor-a mouse antibody (mAb) (Clone F3)
Product Details
- Cat. No.
- 61035
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
ER-a (estrogen receptor a) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding and activation of transcription. ERa localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer and osteoporosis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: F3
- Isotype: IgG1
Handling
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Chromatin Immunoprecipitation (ChIP)
- Immunoprecipitation (IP)
- Western Blotting (WB)