Product & ReviewsAntibodies
Estrogen Receptor b mouse antibody (mAb) (Clone CO1531)
Product Details
- Cat. No.
- 39767
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
ERb (estrogen receptor b) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding and activation of transcription. ERb localizes to the nucleus where it may form a homodimer or a heterodimer with ER alpha. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer and osteoporosis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: CO1531
- Isotype: IgG2a
Handling
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)