Product & ReviewsAntibodies
EZH2 rabbit antibody (pAb)
Product Details
- Cat. No.
- 39901
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
EZH2 is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein, and contains a SET domain that catalyzes the methylation of histone H3 at lysine 27. Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and SUZ12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. Deregulation of EZH2 is linked to a variety of cancers.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
- Isotype: Serum
Handling
- Quantity: 100 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Chromatin Immunoprecipitation (ChIP)
- Immunoprecipitation (IP)
- Western Blotting (WB)