Product & ReviewsAntibodies

EZH2 rabbit antibody (pAb), sample

Product Details

Cat. No.
39934
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Active Motif

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Description

EZH2 is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein, and contains a SET domain that catalyzes the methylation of histone H3 at lysine 27. Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and SUZ12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. Deregulation of EZH2 is linked to a variety of cancers.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse
  • Isotype: IgG

Handling

  • Quantity: 10 ul
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Western Blotting (WB)
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