Product & ReviewsAntibodies

FGR (6G2) Antibody

Product Details

Cat. No.
252859
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

FGR (Gardner-Rasheed feline sarcoma viral oncogene homolog) is a member of the Src family of protein tyrosine kinases (PTKs). FGR contains N-terminal sites for myristylation and palmitylation, a PTK domain, SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse
  • Antigen: Purified recombinant fragment of human FGR expressed in E. coli.
  • Clone: 6G2
  • Isotype: Mouse IgG1
  • Gene: P09769

Handling

  • Quantity: 0.1 ml
  • Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.

Applications

  • Western Blotting (WB)
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