Product & ReviewsAntibodies

Fibulin-5 Antibody

Product Details

Cat. No.
251307
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Fibulin-5 promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Fibulin-5 is a vascular ligand for integrin receptors and may play a role in vascular development and remodeling. Defects in fibulin-5 are a cause of autosomal dominant cutis laxa (ADCL). Hereditary cutis laxa refers to a heterogeneous group of connective tissue disorders characterized by cutaneous abnormalities and variable systemic manifestations. The most constant clinical feature is loose skin, sagging over the face and trunk.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Bovine, Chicken, Dog (Canine), Horse (Equine), Human, Mouse, Pig (Swine), Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human fibulin-5.
  • Isotype: Rabbit Ig
  • Gene: Q9UBX5

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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