FLRT2 Rabbit pAb
Product Details
- Cat. No.
- A17668
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - FLRT2 antibody (A17668)
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Description
This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Mouse
