FMR1 (4G9) Antibody
Product Details
- Cat. No.
- 252868
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
"FMR1 (Fragile X mental retardation protein 1) is an RNA-binding protein. FMR1 associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. "
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human FMR1 expressed in E. coli.
- Clone: 4G9
- Isotype: Mouse IgG1
- Gene: Q06787
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)