FPR1 antibody
Product Details
- Cat. No.
- orb13410
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot analysis of mouse liver (lane 1), mouse spleen (lane 2), rat kidney (lane 3), mouse thymus (lane 4), human breast cancer (lane 5), human lung cancer (lane 6) using FPR1 antibody (1 ug/ml)
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Description
FPR1 (Formyl Peptide Receptor 1) is a Protein Coding gene. Diseases associated with FPR1 include Susceptibility To Localized Juvenile Periodontitis and Periodontitis 1; Juvenile. Among its related pathways are Peptide ligand-binding receptors and Innate Immune System. GO annotations related to this gene include G-protein coupled receptor activity and RAGE receptor binding. An important paralog of this gene is FPR2. FPR1 High affinity receptor for N-formyl-methionyl peptides (fMLP); which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Pig (Swine), Rat
- Clone: NULL
- Conjugate: Unconjugated
- Isotype: IgG
- Gene: 2357
Handling
- Quantity: 100 ?g
- Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
- Buffer: 10 mM PBS; 0.02% sodium azide
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
- Western Blotting (WB)
