Product & ReviewsAntibodies
GAD-67 Antibody
Product Details
- Cat. No.
- 251665
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
67 kDa glutamic acid decarboxylase (GAD-67) catalyzes the production of GABA, the main inhibitory neurotransmitter in the central nervous system. Defects in GAD-67 are the cause of cerebral palsy spastic quadriplegic type 1 (CPSQ1), a non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest symmetrical, non-progressive spasticity and no adverse perinatal history or obvious underlying alternative diagnosis. Developmental delay, mental retardation and sometimes epilepsy can be part of the clinical picture.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Dog (Canine), Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GAD-67.
- Isotype: Rabbit Ig
- Gene: Q99259
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)