Gamma-synuclein (1H10) Antibody
Product Details
- Cat. No.
- 252664
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
SNCG (Gamma-synuclein) is a 127-amino acid protein (~14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein. Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical and breast cancer, but rarely expressed in tumor-matched non-neoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of SNCG expressed in E. coli.
- Clone: 1H10D2
- Isotype: Mouse IgG1
- Gene: O76070
Handling
- Quantity: 0.1 mg
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)