Product & ReviewsAntibodies
GHR Antibody
Product Details
- Cat. No.
- 250665
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The growth hormone receptor (GHR) is the receptor for pituitary gland growth hormone involved in regulating postnatal body growth. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and is a modulator/inhibitor of GH signaling. Binding of GH to the receptor activates the JAK2/STAT5 pathway. Defects in GHR are a cause of Laron dwarfism.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse, Pig (Swine), Rat, Sheep (Ovine)
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GHR.
- Isotype: Rabbit Ig
- Gene: P10912
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)