GLP-1 (A2) Antibody
Product Details
- Cat. No.
- 250244
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Glucagon-like peptide 1 (7-36)amide (GLP-1 (7-36)amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody binds the free N-terminus of GLP-1 (7-37) and GLP-1 (7-36)amide and shows <0.2% cross-reactivity with GLP-1 (9-36)amide, glucagon and human GIP. The antibody cross-reacts with Liraglutide, 0.25% with GLP-1 (1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. This antibody can be used in a sandwich ELISA for exendin-4.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: KLH-conjugated synthetic [Cys18]-GLP-1(7-17) adsorbed onto aluminum hydroxide gel
- Clone: 10
- Isotype: Mouse IgG2a
- Gene: P01275
Handling
- Quantity: 0.2 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)