GluR1 Antibody
Product Details
- Cat. No.
- 253162
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The glutamate receptor 1, a homo- or heterotetramer is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Phosphorylation of Ser831 has been linked to synaptic plasticity as well s learning and memory.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of rat GluR2.
- Isotype: Mouse IgG1
- Gene: P19490
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)