Product & ReviewsAntibodies

GluR1 (Ser831) Antibody

Product Details

Cat. No.
252547
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

The glutamate receptor 1, a homo- or heteroteramer, is an Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Phosphorylation of Ser831 has been linked to synaptic plasticity as well s learning and memory

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Chicken, Dog (Canine), Human, Rat
  • Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser831 of rat GluR1-subunit.
  • Isotype: Rabbit Ig
  • Modifications: Phosphospecific Antibody
  • Gene: P19490

Handling

  • Quantity: 0.1 ml
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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