GLUT2 Antibody
Product Details
- Cat. No.
- 250672
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Glucose transporter type 2 (GLUT2 or SLC2A2) is a facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells. GLUT2 is also part of the glucose-sensing mechanism of the beta cell and participate with the Na+/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Defects in GLUT2 are the cause of Fanconi-Bickel syndrome, characterized by hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Monkey, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GLUT2.
- Isotype: Rabbit Ig
- Gene: P11168
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)