Product & ReviewsAntibodies
Glutamate Decarboxylase Antibody
Product Details
- Cat. No.
- 250502
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
GAD65, an autoantigen in type I diabetes, is transiently activated in response to the demand for extra GABA in neurotransmission, and cycles between an active holo form and an inactive apo form. An inherently mobile catalytic loop promotes a side reaction that results in cofactor release and GAD65 autoactivation.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human glutamate decarboxylase.
- Isotype: Rabbit Ig
- Gene: Q05329
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)