Product & ReviewsAntibodies

GOAT ANTI HUMAN BIM (C-TERMINAL)

Product Details

Cat. No.
AHP2074
Type
Primary Antibody
Clonality
Polyclonal
Host
Goat
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Bio-Rad

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Description

Goat anti Human BIM antibody recognizes an epitope within the C-terminal (CT) region of the AD, ACD and ABCD isoforms of human BIM, otherwise known as Bcl-2 interacting mediator of cell death.BIM is an apoptotic activator protein and member of the Bcl-2 family, which forms heterodimers with several anti-apoptotic proteins including BCL2, BHRF1, and MCL1, but not with the pro-apoptotic proteins BAD, BAX or BAK. BIM can be induced by nerve growth factor (NGF) and also by forkhead transcription factor FKHR-L1, implicating BIM in both neuronal and lymphocyte apoptosis.

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Human
  • Isotype: Polyclonal IgG

Handling

  • Quantity: 0.1 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: TRIS buffered saline, 0.02% Sodium Azide, 0.5% BSA

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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