Product & ReviewsAntibodies
GOAT ANTI HUMAN BIM (C-TERMINAL)
Product Details
- Cat. No.
- AHP2074
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Goat
Description
Goat anti Human BIM antibody recognizes an epitope within the C-terminal (CT) region of the AD, ACD and ABCD isoforms of human BIM, otherwise known as Bcl-2 interacting mediator of cell death.BIM is an apoptotic activator protein and member of the Bcl-2 family, which forms heterodimers with several anti-apoptotic proteins including BCL2, BHRF1, and MCL1, but not with the pro-apoptotic proteins BAD, BAX or BAK. BIM can be induced by nerve growth factor (NGF) and also by forkhead transcription factor FKHR-L1, implicating BIM in both neuronal and lymphocyte apoptosis.
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Human
- Isotype: Polyclonal IgG
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: TRIS buffered saline, 0.02% Sodium Azide, 0.5% BSA
Applications
- ELISA (ELISA)
- Western Blotting (WB)