Product & ReviewsAntibodies
GOAT ANTI HUMAN TNF ALPHA
Product Details
- Cat. No.
- AHP1212
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Goat
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Description
Goat anti Human TNF alpha antibody recognizes human Tumour Necrosis Factor alpha (TNF–alpha), a 17.4kDa multi-functional pro-inflammatory cytokine primarily secreted by macrophages, but also produced by T and B lymphocytes, activated monocytes and fibroblasts.TNF-alpha exists in both a transmembrane and mature soluble form and has many biological properties, including activation of transcription factor NF-kappaB, the induction of apoptosis in various tumour cell lines and the stimulation of cell differentiation and proliferation under certain conditions. TNF-alpha also plays a role in inflammation, septic shock, autoimmune disease and rheumatoid arthritis.
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Human
- Isotype: Polyclonal IgG
Handling
- Quantity: 0.1 mg
- Storage: -20ºC only
- Buffer: Phosphate buffered saline
Applications
- ELISA (ELISA)
- Functional Studies (Func)
- Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
- Western Blotting (WB)