Product & ReviewsAntibodies
GRK1 Antibody
Product Details
- Cat. No.
- 251453
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
G protein-coupled receptor kinase 1 (GRK1, rhodopsin kinase) phosphorylates rhodopsin thereby initiating its deactivation. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination. Defects in GRK1 are a cause of congenital stationary night blindness Oguchi type 2 (CSNBO2). It is a non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Chimpanzee, Human, Monkey, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GRK1.
- Isotype: Rabbit Ig
- Gene: Q15835
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)