Product & ReviewsAntibodies
GRK2 Rabbit mAb
Product Details
- Cat. No.
- A4443
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - GRK2 Rabbit mAb (A4443)
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Description
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
