HAMSTER ANTI MOUSE CD103
Product Details
- Cat. No.
- MCA4705GA
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Hamster
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Description
Hamster anti Mouse CD103 antibody, clone 2E7 recognizes mouse CD103, otherwise known as integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule αEβ7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The αEβ7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocyes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells. Hamster anti Mouse CD103 antibody, clone 2E7 is expected to also recognize the intact αEβ7 complex.
Biological Information
- Clonality: Monoclonal
- Host: Hamster
- Reactivity: Mouse
- Isotype: IgG
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- Flow Cytometry (FC)
- Immunofluorescence (IF)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
- Immunoprecipitation (IP)