Product & ReviewsAntibodies
HAMSTER ANTI MOUSE CD27
Product Details
- Cat. No.
- MCA4701
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Hamster
Description
Hamster anti Mouse CD27 antibody, clone LG.3A10 recogniszes mouse, rat and human CD27, a member of the tumour necrosis factor receptor superfamily. It is expressed in the thymus and spleen, but not in non-lymphoid tissues. CD27 acts as a ligand for CD70, which is expressed in T and B cells, and acts as a costimulatory signal in lymphocyte proliferation and immunoglobulin production.CD27 lacks a death domain in its short cytoplasmic tail, but can induce apoptosis by binding with the apoptosis regulatory protein Siva (also known as CD27-binding protein).
Biological Information
- Clonality: Monoclonal
- Host: Hamster
- Reactivity: Human, Mouse, Rat
- Isotype: IgG
Handling
- Quantity: 0.25 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- Flow Cytometry (FC)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
- Immunoprecipitation (IP)