Product & ReviewsAntibodies

HAMSTER ANTI MOUSE CD27

Product Details

Cat. No.
MCA4701
Type
Primary Antibody
Clonality
Monoclonal
Host
Hamster
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Bio-Rad

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Description

Hamster anti Mouse CD27 antibody, clone LG.3A10 recogniszes mouse, rat and human CD27, a member of the tumour necrosis factor receptor superfamily. It is expressed in the thymus and spleen, but not in non-lymphoid tissues. CD27 acts as a ligand for CD70, which is expressed in T and B cells, and acts as a costimulatory signal in lymphocyte proliferation and immunoglobulin production.CD27 lacks a death domain in its short cytoplasmic tail, but can induce apoptosis by binding with the apoptosis regulatory protein Siva (also known as CD27-binding protein).

Biological Information

  • Clonality: Monoclonal
  • Host: Hamster
  • Reactivity: Human, Mouse, Rat
  • Isotype: IgG

Handling

  • Quantity: 0.25 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • Flow Cytometry (FC)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
  • Immunoprecipitation (IP)
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