HCV-Core Antibody
Product Details
- Cat. No.
- 250683
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The p21 core protein from Hepatitis C virus (HCV) packages viral RNA to form a viral nucleocapsid and promotes virion budding . p21 modulates viral translation initiation and regulates many host cellular activities by interacting with HCV IRES and 40S ribosomal subunit. p21 also regulates host cellular functions that prevent the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. p21 plays an important role in the virus-mediated cell transformation leading to hepatocellular carcinomas.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Virus
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of HCV p21 core protein.
- Isotype: Rabbit Ig
- Gene: P26664
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)