Product & ReviewsAntibodies

HDAC3 (3A7B) Antibody

Product Details

Cat. No.
252812
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

HDAC3 (Histone deacetylase 3) is a histone deacetylase protein. Histones play a critical role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: Purified recombinant fragment of HDAC3(aa224-428) expressed in E. coli.
  • Clone: 3A7B5
  • Isotype: Mouse IgG1
  • Gene: O15379

Handling

  • Quantity: 0.1 ml
  • Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.

Applications

  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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