HDAC4 (7B2) Antibody
Product Details
- Cat. No.
- 252949
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
HDAC4 (Histone deacetylase 4) is a member of the histone deacetylase family. Histones play a critical role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: "Purified recombinant fragment of human HDAC4 expressed in E. coli. <br>"
- Clone: 7B2
- Isotype: Mouse IgG1
- Gene: P56524
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)