Helios-PB, 22F6, 50 Tests, RUO
Product Details
- Cat. No.
- B49311
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Hamster
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Description
Helios belongs to the Ikaros transcription factor family. Members of this family are DNA binding proteins containing two-zinc finger N terminal domains and protein binding domain. Helios expression is restricted to the T lymphocytes lineage. Helios is suggested to play an important role in CD4+CD25+FoxP3+ regulatory cells. It has been shown that Helios up-regulates the expression of FoxP3 expression by binding to the FoxP3 promoter. Helios is a highly conserved transcription factor that has 97% sequence homology between human and mice.*Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
Biological Information
- Clonality: Monoclonal
- Host: Hamster
- Reactivity: Human
- Antigen: Helios
- Clone: 22F6
- Conjugate: Pacific Blue*
- Isotype: IgG
Handling
- Quantity: 50 tests
Applications
- Flow Cytometry (FC)