Product & ReviewsAntibodies
HERC5 Rabbit pAb
Product Details
- Cat. No.
- A14889
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - HERC5 antibody (A14889)
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Description
This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
