HERG Antibody
Product Details
- Cat. No.
- 252174
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Potassium voltage-gated channel subfamily H member 2 (HERG) is the pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. The HERG channel properties are modulated by cAMP and subunit assembly. HERG mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1. Defects in HERG are the cause of long QT syndrome type 2 (LQT2). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to exercise or emotional stress.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human HERG.
- Isotype: Rabbit Ig
- Gene: Q12809
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)