Product & ReviewsAntibodies
HHV-8 VIL-6 Antibody
Product Details
- Cat. No.
- 251352
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Human herpesvirus 8 (HHV-8 or KSHV, Kaposi's sarcoma-associated herpesvirus) has been associated with classical, endemic (African), and AIDS-related Kaposi's sarcoma (KS), body cavity-based primary effusion lymphomas, and multicentric Castleman's disease (MCD). KSHV encodes more than 85 protein-coding genes. ORF K2 encodes a viral form of interleukin-6 (vIL-6), a cytokine that promotes the growth of KS and myeloma cells and is found at elevated levels in MCD lesions and patient sera. vIL-6 shares 25% amino-acid identity with human cellular IL-6.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Virus
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region ORF K2 from HHV-8 VIL-6.
- Isotype: Rabbit Ig
- Gene: Q76SK3; O40918
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)