Product & ReviewsAntibodies
Hirudin (2D7) Antibody
Product Details
- Cat. No.
- 250211
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Hirudin is a highly effective and very specific anticoagulant which inhibits formation of fibrin and activation of factors V, VIII and XIII by forming irreversible, noncovalent 1:1 complexes with alpha-thrombin. Hirudin is used to treat heparin-induced thrombocytopenia (Refludan/Hoechst Marion Roussel). Hirudin is a 7 kDa protein naturally originating from the medical leech Hirudo medicinalis. This antibody recognizes hirudin under both native and reducing conditions in SDS-PAGE. The antibody binds to an epitope in the C-terminal region of hirudin with an affinity of 450 nM.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Antigen: Recombinant hirudin (rHV2) produced in S. cerevisiae and coupled to diphteria toxoid.
- Isotype: mouse IgG1
- Gene: P01050
Handling
- Quantity: 0.1 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)