Product & ReviewsAntibodies
Histone H3K27me1 rabbit antibody (pAb), sample
Product Details
- Cat. No.
- 39378
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Histone H3 is subject to a variety of post-translational modifications (acetylation, methylation, phosphorylation) that affect packaging and accessibility of genomic DNA. Methylation of lysine 27 at histone H3 is carried out by the EZH2 methyltransferase, part of the Polycomb protein complex. The Polycomb complex silences gene expression by creating localized regions of facultative heterochromatin, and methylation of lysine 27 is part of this process.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Not Species Specific, Human
- Isotype: Serum
Handling
- Quantity: 10 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Dot Blot (DB)
- Immunofluorescence (IF)
- Western Blotting (WB)