Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Methylation of histone H3 at lysine 4 is linked to transcriptional activation through the recruitment of a number of downstream effector proteins (e.g. CHD1, ING2, Isw1, NURF301, WDR5). Lysine 4 methylation is dependant upon the monoubiquitylation of the C-terminus of histone H2A.
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Not Species Specific, Human, Mouse
- Isotype: Serum
- Quantity: 10 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Chromatin Immunoprecipitation (ChIP)
- Dot Blot (DB)
- Western Blotting (WB)
