Product & ReviewsAntibodies

Histone H3K4me3 rabbit antibody (pAb), sample

Product Details

Cat. No.
39916
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Active Motif

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Description

Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Methylation of histone H3 at lysine 4 is linked to transcriptional activation through the recruitment of a number of downstream effector proteins (CHD1, Isw1, ING2, WDR5). At least one protein that selectively binds histone H3 trimethylated at lysine 4 has also been reported (NURF301). Trimethyl lysine 4 is enriched at the transcriptional start site of activated genes. Lysine 4 methylation is dependant upon the monoubiquitylation of the C-terminus of histone H2A.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Not Species Specific, Human, Yeast
  • Isotype: IgG

Handling

  • Quantity: 10 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Chromatin Immunoprecipitation (ChIP)
  • Dot Blot (DB)
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Western Blotting (WB)
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