Product & ReviewsAntibodies
Histone H3K4me3 rabbit antibody (pAb), sample
Product Details
- Cat. No.
- 39916
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Methylation of histone H3 at lysine 4 is linked to transcriptional activation through the recruitment of a number of downstream effector proteins (CHD1, Isw1, ING2, WDR5). At least one protein that selectively binds histone H3 trimethylated at lysine 4 has also been reported (NURF301). Trimethyl lysine 4 is enriched at the transcriptional start site of activated genes. Lysine 4 methylation is dependant upon the monoubiquitylation of the C-terminus of histone H2A.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Not Species Specific, Human, Yeast
- Isotype: IgG
Handling
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Chromatin Immunoprecipitation (ChIP)
- Dot Blot (DB)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Western Blotting (WB)