Product & ReviewsAntibodies

Histone H3K9me0 mouse antibody (mAb) (Clone 9B1-2G6), sample

Product Details

Cat. No.
61400
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Active Motif

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Description

Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression. Methylation of lysines occur as four states: unmethylated (me0), monomethyl (me1), dimethyl (me2) and trimethyl (me3). The me0 state of lysine is recognized as biologically relevant and a number of proteins containing PhD fingers, ADD and WD40 domains are known to associate with unmodified lysines.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Not Species Specific, Human
  • Clone: 9B1-2G6
  • Isotype: IgG1

Handling

  • Quantity: 10 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Western Blotting (WB)
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