Histone H3R17me2a (asymmetric) rabbit antibody (pAb)
Product Details
- Cat. No.
- 39709
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation. These modifications play a major role in regulating gene expression. Methylation of arginine 17 by the co-activator protein CARM1/PRMT4 is involved with transcriptional activation by nuclear receptors.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Not Species Specific, Human
- Isotype: IgG
Handling
- Quantity: 100 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Dot Blot (DB)
- Western Blotting (WB)