HLA-ABC-FITC, B9.12.1, 2 mL, ASR
Product Details
- Cat. No.
- IM1838U
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
HLA-A, -B, and -C are major histocompatibility complex (MHC)-class I antigens. Like other class I molecules (i.e. HLA-E, -F, -G), HLA-A, -B, and -C are heterodimers consisting of a 40 – 45 kDa transmembrane glycoproteic α-chain, noncovalently combined to the invariant β2-microglobulin. All class I molecules have conserved, monomorphic domains, but are also characterized by their extensive degree of allelic polymorphism. MHC molecules play a central role in the immune response. They are involved in the maturation of T cell repertoire, in the activation of T lymphocytes by presentation of xenogenic peptides or in the allogenic response. HLA-A, -B and -C are "classical" MHC Class I molecules and are expressed on the surface of most nucleated human cell types.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Baboon, Cynomolgus Monkey, Human, Rhesus Monkey
- Antigen: HLA-ABC
- Clone: B9.12.1
- Conjugate: FITC
- Isotype: IgG2a
Handling
- Quantity: 2 mL
Applications
- Flow Cytometry (FC)