HLA-E Rabbit pAb
Product Details
- Cat. No.
- A8429
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - HLA-E antibody (A8429)
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Description
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
