HNF-3a / FOXA1 mouse antibody (mAb) (Clone 2F83)
Product Details
- Cat. No.
- 39837
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
HNF-3a (Hepatocyte nuclear factor 3 alpha, forkhead box A1, FoxA1) is a homeodomain containing transcription factor and is a member of the Hepatocyte Nuclear Factor family (HNF-1a, HNF-1b, HNF-3a, HNF-3b, HNF-3γ, HNF-4a, HNF-4γ, HNF-6a and HNF-6b), whose members regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3 members bind to DNA as monomers using a winged helix DNA-binding domain. HNF-3a and HNF-3γ have also been shown to be involved in events such as gastrulation and body axis formation. HNF-3a modulates transcriptional activity of the estrogen receptor and is involved in the development of multiple endoderm-derived organ systems such as liver, pancreas, lung and prostate.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Clone: 2F83
- Isotype: IgG
Handling
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Chromatin Immunoprecipitation (ChIP)
- Immunohistochemistry (IHC)
- Western Blotting (WB)