Product & ReviewsAntibodies
HP1b mouse antibody (mAb) (Clone 1MOD-1A9)
Product Details
- Cat. No.
- 39979
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
HP1 beta (Heterochromatin Protein 1 beta, Chromobox protein 1, CBX1) is one of the mammalian homologues of Drosophila HP1, first identified through its role in the maintenance of regions of the genome in a heterochromatic state. HP1 beta contains a chromo domain and a chromo shadow domain. Through the chromo domain, HP1 proteins are recruited to regions of chromatin that exhibit methylation of lysine 9 of histone H3. Interaction between HP1 beta and the lamin B receptor can facilitate the sequestration of heterochromatin to the nuclear envelope.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Clone: 1MOD-1A9
- Isotype: IgG1
Handling
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunofluorescence (IF)
- Immunoprecipitation (IP)
- Western Blotting (WB)