Product & ReviewsAntibodies
HSP-60 Antibody
Product Details
- Cat. No.
- 250700
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Heat shock protein 60 (HSP-60) is implicated in mitochondrial protein import and macromolecular assembly. HSP-60 facilitates the correct folding of imported proteins. HSP-60 also prevents misfolding and promotes refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. Defects in HSP-60 are a cause of spastic paraplegia autosomal dominant type 13 (SPG13), a degenerative spinal cord disorder. Defects in HSP-60 are the cause of leukodystrophy hypomyelinating type 4 (HLD4 or MitCHAP-60 disease).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human HSP-60.
- Isotype: Rabbit Ig
- Gene: P10809
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)