Product & ReviewsAntibodies
HSP-60 Antibody
Product Details
- Cat. No.
- 251756
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Heat shock protein 60 (HSP-60) is involved in mitochondrial protein import and macromolecular assembly. HSP-60 facilitates the correct folding of imported proteins. HSP-60 also prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. Defects in HSPD1 are a cause of spastic paraplegia autosomal dominant type 13 (SPG13). Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Chicken, Human, Rat
- Antigen: Recombinant human HSP-60.
- Clone: SJ-60
- Isotype: Mouse IgG1
- Gene: P10809
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)