HUMAN ANTI ADALIMUMAB

Human Anti-Adalimumab Antibody, clone AbD18654_hIgG1, is a high affinity anti-idiotypic antibody that specifically recognizes the adalimumab monoclonal antibody and inhibits the binding of adalimumab to its target, TNFα. The antibody can be used to measure the levels of adalimumab and biosimilar products in bioanalytical assays.Clone AbD18654_hIgG1 can be used to develop and calibrate immune response assays to measure the anti-drug antibody (ADA) response in patient serum.Adalimumab (branded as Humira) is a fully human monoclonal antibody (IgG1/kappa) approved for the treatment of ankylosing spondylitis, Crohn’s disease, psoriasis and several forms of arthritis. The antibody is specific for TNFα, and acts by blocking the activation of TNF receptors by TNFα. This inactivation down-regulates the inflammatory reactions associated with autoimmune diseases.View a summary of all Anti-Adalimumab Antibodies.

• Clonality: Monoclonal
• Host: Human
• Isotype: IgG1

• Quantity: 0.1 mg
• Storage: +4ºC, -20ºC if preferred
• Buffer: Phosphate buffered saline, 0.01% Thiomersal

• ELISA (ELISA)