HUMAN ANTI CD52 (ALEMTUZUMAB BIOSIMILAR)

Human Anti-CD52 Antibody, clone Campath-1H is a research grade biosimilar of the monoclonal antibody drug alemtuzumab. It is a recombinant human IgG1 kappa antibody with variable regions from the therapeutic antibody Campath-1H. Human Anti-CD52 Antibody is for research use only. It is suitable as a reference standard in a pharmacokinetic (PK) bridging ELISA with anti-alemtuzumab antibodies, for example HCA198 and HCA175. It can also be used as capture and detection reagent in an anti-drug antibody (ADA) bridging ELISA, with an anti-alemtuzumab antibody in IgG1 format as reference standard, for example HCA175. Alemtuzumab is a drug used in the treatment of chronic lymphocytic leukemia (CLL), cutaneous T-cell lymphoma (CTCL) and T-cell lymphoma. Alemtuzumab is also used in some conditioning regimes for bone marrow transplantation, kidney transplantation and islet cell transplantation along with clinical trial protocols for treatment of certain autoimmune diseases including multiple sclerosis. This product is NOT FOR THERAPEUTIC USE.View a summary of supporting anti-alemtuzumab antibody products

• Clonality: Monoclonal
• Host: Human
• Reactivity: Human
• Isotype: IgG1

• Quantity: 0.2 mg
• Storage: +4ºC, -20ºC if preferred
• Buffer: Phosphate buffered saline, 0.02% Proclin 300

• ELISA (ELISA)