Product & ReviewsAntibodies
HUMAN ANTI HUMAN DJ-1 (OXIDIZED AT C106)
Product Details
- Cat. No.
- HCA024
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Human
Western blot demonstrating specifity of HCA024 for DJ-1 oxidized at C106
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Description
Human anti Human DJ-1 antibody, clone AbD03055 recognizes the human DJ-1 oncogene only when it is oxidized on cysteine C106. DJ-1 plays roles in transcriptional regulation and reaction to anti-oxidative stress. The oxidation status of DJ-1, particularly at C106, modulates the function of DJ-1 (Canet-Avilés et al. 2004). De-regulation of DJ-1 oxidation appears to be connected to the onset of conditions such as Parkinson's Disease (Abou-Sleiman et al. 2003).
Biological Information
- Clonality: Monoclonal
- Host: Human
- Reactivity: Human
- Isotype: HuCAL Fab bivalent
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.01% Thiomersal
Applications
- ELISA (ELISA)
- Western Blotting (WB)
