HUMAN ANTI INFLIXIMAB
Product Details
- Cat. No.
- HCA212
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Human
HCA212 Specificity ELISA
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Description
Human Anti-Infliximab, clone AbD17837, is an anti-idiotypic antibody that specifically recognizes the infliximab monoclonal antibody and inhibits the binding of infliximab to its target. It can be used in bioanalytical assays to measure the levels of infliximab and biosimilar products, such as Inflectra and Renflexis, in patient samples.Infliximab (branded as Remicade) is a chimeric monoclonal antibody drug (IgG1/kappa) that has been approved for treatment of psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab is directed against Tumour Necrosis Factor Alpha (TNFα) and acts by blocking the binding of this cytokine to its receptors. Infliximab also induces apoptosis of TNFα expressing T-lymphocytes.View a summary of all Anti-Infliximab Antibodies.
Biological Information
- Clonality: Monoclonal
- Host: Human
- Isotype: HuCAL Fab monovalent
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.01% Thiomersal
Applications
- ELISA (ELISA)
