Product & ReviewsAntibodies
ICAD Antibody
Product Details
- Cat. No.
- 250705
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Inhibitor of CAD (ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45 is an inhibitor of the caspase-activated DNase. Caspase-activated deoxyribonuclease (CAD) is also designated as DNA fragmentation factor 40 kDa subunit (DFF-40) and caspase-activated Dnase. CAD is a nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. ICAD is a heterodimer of DFFA and DFFB. Caspase-3 cleaves ICAD at 2 sites to generate an active factor.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse ICAD.
- Isotype: Rabbit Ig
- Gene: O00273
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)